高血压用药基因检测论文

豆丁网是面向全球的中文社会化阅读分享平台，拥有商业,教育,研究报告,行业资料,学术论文,认证考试 ... 2017-06-23实质审查的生效实质审查的生效2020-03-27授

确诊高血压的患者,需要长期口服降压药物,具体选择哪种降压药物,可以通过高血压用药基因检测进行选择,不同的人对同样的降压药物产生不同的效果,这主要是由于基因所决定的。基","subtitleWithAvatar":[{"text":"李海涛 副主任医师 保定市第二医院 三甲 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高血压个体化用药基因检测及临床意义. 据世界卫生组织（WHO）统计资料显示，2012 年全球心血管疾病死亡人数约为 1700 万，占慢性病死亡人数的 46%，其中

目前,经过 CFDA 三类医疗器械批准的高血压用药基因检测产品为荧光 PCR 和基因芯片原理,其中荧光 PCR 技术是主流技术,与其操作便捷、检测快速、结果准确,判读

药物基因组学、基因检测需求、基因检测可行性、进展 Repconex 指导个性化用药 高血压定义 •高血压是一种动脉压升高为主要特征，可并发心、脑、肾、视网膜等器官损伤及代谢改变的临床综合征。•《

对于选用何种降压机制的药物，能在降低高血压药物副作用的同时，还能提高用药有效性，一直备受临床的关注。临床实践发现对于相同的抗高血压药物，不同患者

治疗高血压的药物在临床上出现的个体反应差异十分普遍,其主要的原因是由于与药物相关的药物代谢酶和受体发生了遗传变异。 医生可根据患者的基因多态性来提供更加合理的药物选择和治

由于单基因高血压有明确的致病原因,针对性的特异治疗往往效果较好。通过检测相关基因是否存在突变,可以对此类患者作出明确的诊断或鉴别诊断,并且能够通过筛查直

原发性高血压易感基因需检测核子基因，利用高通量测序技术全面筛查与高血压相关的22个基因26个突变点，如ACE、STK39、NOS3等。 原发性高血压是指一种与

常见的和高血压药物相关的基因包括CYP2D6 、ADRB1 、CYP2C9 、AGTR1 、ACE 等基因，可以指导高血压药物应用，帮助高血压患者选择合适的降压药！但对于高血压药物基因检测的结果，