流产绒毛基因检测论文

原位杂交技术在检测染色体非整倍体畸变中的价值。 方法应用13、16、18、21、22、X和Y染色体特异性DNA探针对150份因早期自然流产行清宫术的患者绒毛

沈晔.全基因组染色体芯片在流产绒毛及死胎遗传学诊断中的应用[J].南京医科大学学报（自然科学版），2018，38（11）：1586-1592 [9] 吴庆华，史惠蓉，王艳

流产以后有时需要针对胚胎的染色体进行检查,以明确流产的原因,检测胚胎染色体的方法包括以下几种。第一,提取绒毛细胞进行培养,然后提取绒毛细胞中的染色体进行分析化验。第二","subtitleWithAvatar":[{"text":"张露 主治医师 山东大学齐鲁医院 三甲 回答时间: 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2019年06月11日","time_new":"时间: 2019年06月11日","timestamp":1677259055,"title":"流产后胚胎染色体检查的方法","type":"article","url":"http://m.youlai.cn/askdzmip/46F5A6MMfFO.html","abstract":"\u0002流产\u0003以后\u0001有\u0001时\u0001需要\u0001针对\u0001胚胎\u0001的\u0001染色体\u0001进行\u0001检查\u0001,\u0001以\u0001明确\u0001流产\u0001的\u0001原因\u0001,\u0002检测\u0003胚胎\u0001染色体\u0001的\u0001方法\u0001包括\u0001以下\u0001几\u0001种\u0001。\u0001第\u0001一\u0001,\u0001提取\u0002绒毛\u0003细胞\u0001进行\u0001培养\u0001,\u0001然后\u0001提取\u0001绒毛\u0001细胞\u0001中\u0001的\u0001染色体\u0001进行\u0001分析\u0001化验\u0001。\u0001第\u0001二\u0001,\u0001直接\u0001提取\u0001绒毛\u0001细胞\u0001,\u0001但是\u0001不\u0001进行\u0001细胞\u0001培养\u0001,\u0001直接\u0001进行\u0001基因\u0001芯片\u0001检测\u0001,\u0001判断\u0001\u0001","replaced":"流产以后有时需要针对胚胎的染色体进行检查，以明确流产的原因，检测胚胎染色体的方法包括以下几种。第一，提取绒毛细胞进行培养，然后提取绒毛细胞中的染色体进行分析化验。第二，直接提取绒毛细胞，但是不进行细胞培养，直接进行基因芯片检测，判断是否存在微缺失和微重复。第三，针对绒毛细胞进行二代测序或单基因病检测，明确是否存在基因突变。"},"meta_di_info":[],"official_struct_abstract":{"from_flag":"disp_site","office_name":"有来医生网"},"site_region":"0","src_id":"6899_8654_6547","trans_res_list":["medical_struct_abstract","medask_struct_abstract","official_struct_abstract"],"ulangtype":1,"ti_qu_related":0.17795621123845,"templateName":"se_st_default","StdStg_new":1599,"disp_summary_lat":"1","wise_search":false,"DispUrl":"m.baidu.com/bh/m/detail/qr_15886320103287846017","is_valid":1,"brief_download":"0","brief_popularity":"0","material_data":{"material_sign1":"4265026251","material_sign2":"1279484781","material_list":[{"key":"nid","value":"0"},{"key":"thread_id","value":"0"}]},"rtset":1560182400,"timeHighlight":1,"cambrian_us_showurl":{"logo":"NULL","title":"有来医生网"},"is_us_showurl":1,"site_sign":"6377359900320292902","url_sign":"18318148265905972077","strategybits":{"OFFICIALPAGE_FLAG":0},"resultData":{"tplData":{"footer":{"footnote":{"source":{"img":null,"source":"有来医生网"}}},"groupOrder":1,"ttsInfo":{"supportTts":false}},"resData":{"tplt":"se_com_default","tpl_sys":"san","env":"pc"},"url_trans_feature":{"antispam_url_ctrl":"0","antispam_chutu_ctrl":"0","struct_cont_sign":"0","struct_simhash":"0","cont_sign":"3873031446","cont_simhash":"611203655474926028","page_classify_v2":"9223372036854792192","m_self_page":"0","m_page_type":"0","rtse_news_site_level":"0","rtse_scs_news_ernie":"-1","rtse_news_sat_ernie":"0","rtse_event_hotness":"0","f_event_score":"0","f_prior_event_hotness":"2","cont_sign_1":"3873031446","struct_cont_sign_1":"0","spam_signal":"400855826489672704","time_stayed":"0","gentime_pgtime":"1560182400","day_away":"1363","ccdb_type":"0","nid":"0","thread_id":"0"}},"strategy":{"tempName_ori":null,"tempName":"se_com_default","type":"result","mapping":null,"tpl_sys":"san","module":"aladdin-san"},"source_name":"有来医生网","posttime":"2019年6月11日","belonging":{"list":"asResult","No":1,"templateName":"se_com_default"},"subtitleWithAvatar":[{"text":"张露 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自然流产绒毛与蜕膜组织中细胞凋亡的研究

据以往研究认为,染色体异常胎多伴有胎盘和绒毛的组织学改变,但有关胎盘组织学诊断的预测价值尚无充足的资料证明.本文对123例妊娠6～19周自然流产胎进行了联合的组织学和细胞

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